New Triterpenoids from the Leaves of Cyclocarya paliurus

Shuai Li; Baosong Cui; Quan Liu; Li Tang; Yongchun Yang; Xiangju Jin; Zhufang Shen

doi:10.1055/s-0031-1280411

Planta Medica, Table of Contents

Planta Med 2012; 78(3): 290-296
DOI: 10.1055/s-0031-1280411

Natural Product Chemistry

Letters
© Georg Thieme Verlag KG Stuttgart · New York

New Triterpenoids from the Leaves of Cyclocarya paliurus

Shuai Li¹ , Baosong Cui¹ , Quan Liu¹ , Li Tang² , Yongchun Yang¹ , Xiangju Jin¹ , Zhufang Shen¹

¹State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P. R. China
²Division of Experimental Therapeutics, Department of Medicine, Columbia University, New York, New York, USA

Abstract

Six new triterpenoids including four new secodammarane triterpenoid glycosides (1–4), an epoxydammarane triterpenoid glycoside (5), and a new secodammarane triterpenoid (6) were isolated from the ethanolic extract of the leaves of Cyclocarya paliurus. The structures of these compounds were elucidated by spectroscopic analysis methods. Compounds 1–6 were evaluated for their inhibitory activities against α-glucosidase, lipase, DPP-IV, and aldose reductase.

Key words

Cyclocarya paliurus - Juglandaceae - triterpenoid - secodammarane type - biological activity

Full Text

References

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Dr. Shuai Li

Institute of Materia Medica, Department of Natural Product Chemistry
Chinese Academy of Medical Sciences and Peking Union Medical College

1 Xian Nong Tan Street

Beijing 100050

P. R. China

Phone: +86 10 63 16 46 28

Fax: +86 10 63 01 77 57

Email: lishuai@imm.ac.cn

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