Download PDF
Synfacts 2011(8): 0879-0879  
DOI: 10.1055/s-0030-1260737
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Diastereoselective Ruthenium-Catalyzed [2+2] Cycloadditions of Allenenes

Contributor(s): Mark Lautens, Stephen G. Newman
M. Gulías, A. Collado, B. Trillo, F. López, E. Oñate, M. A. Esteruelas*, J. L. Mascareñas*
Universidad de Santiago de Compostela, Universidad de Zaragoza and Institiuto de Química Orgánica General, Madrid, Spain
Further Information

Publication History

Publication Date:
20 July 2011 (online)

    Permissions and Reprints

Significance

Polyunsaturated substrates can ­often undergo a variety of different cycloaddition reactions depending on the catalyst and conditions, allowing a divergent approach to complex, stereochemically rich molecules. The authors present a novel [2+2] mode of reactivity of tethered allenenes to produce bicyclo[3.2.1]heptanes.