Download PDF
Synfacts 2011(7): 0762-0762  
DOI: 10.1055/s-0030-1260637
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of a Chiral Bidentate sp²-N Ligand

Contributor(s): Mark Lautens, Patrick T. Franke
K. Miyata, H. Kutsuna, S. Kawakami, M. Kitamura*
Nagoya University, Japan
Further Information

Publication History

Publication Date:
17 June 2011 (online)

    Permissions and Reprints

Significance

In this paper the authors describe the preparation of a new family of chiral bidentate sp²-N ligands and demonstrated its utility in a Ru-catalyzed enantioselective dehydrative C-, N-, and O-allylation. Notable is the synthesis of highly enantioslective five- and six-membered cyclo­alkanes and N- and O-heterocycles - potential key intermediates for biologically active natural products.