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Synfacts 2011(6): 0612-0612  
DOI: 10.1055/s-0030-1260409
Synthesis of Materials and Unnatural Products
© Georg Thieme Verlag Stuttgart ˙ New York

Polyaromatic Furans from Diynyl-1,6-diols

Contributor(s): Timothy M. Swager, Jan M. Schnorr
Y.-H. Wang, H. Liu, L.-L. Zhu, X.-X. Li, Z. Chen*
Renmin University of China, Beijing and Institute of Chemistry, Chinese Academy of Sciences, Beijing, P. R. of China
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Publication History

Publication Date:
19 May 2011 (online)

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Significance

The authors describe a base-­catalyzed reaction to obtain polyaromatic furan derivatives from diynyl-1,6-diols. The reaction was optimized using the model reaction to form the phenyl derivative 2. The described conditions can be used to access a variety of related compounds with substituted phenyl (e.g. 4a-c) or heteroaromatic groups (6).