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Synfacts 2010(11): 1254-1254  
DOI: 10.1055/s-0030-1258744
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Ruthenium-Catalyzed Asymmetric Transfer Hydrogenation to Chiral Primary Amines

Contributor(s): Hisashi Yamamoto, Zhi Li
D. Guijarro*, Ó. Pablo, M. Yus*
Universidad de Alicante, Spain
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Publication History

Publication Date:
21 October 2010 (online)

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Significance

This report describes a ruthenium-catalyzed highly diastereoselective transfer hydrogenation, which converts chiral N-(tert-butanesulfinyl)ketimines into chiral α-branched primary amines with high yield and enantioenrichment.