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Synfacts 2010(11): 1246-1246  
DOI: 10.1055/s-0030-1258734
Synthesis of Materials and Unnatural Products
© Georg Thieme Verlag Stuttgart ˙ New York

Swollen-up Molecules by Fragmentation

Contributor(s): Timothy M. Swager, Youhei Takeda
J. Hierold, A. Gray-Weale, D. W. Lupton*
Monash University, Clayton, Australia
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Publication History

Publication Date:
21 October 2010 (online)

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Significance

A Grob-type C-C bond fragmentation of β-keto cycloalkanones using polyols under mild conditions giving polyesters bearing Michael acceptors is described. The validity of this method is also demonstrated by preparation of the fourth generation dendrimer through fragmentation thio-Michael addition sequences.