A Novel and One-Pot Multicomponent
Approach to the Synthesis of Dihyroindeno[1,2-b]pyrroles and Indeno[2′,1′:4,5]pyrrolo[1,2-a]-Fused 1,3-Diazaheterocycles

Abdolali Alizadeh; Ameneh Zarei; Atieh Rezvanian

doi:10.1055/s-0030-1258383

PAPER

A Novel and One-Pot Multicomponent Approach to the Synthesis of Dihyroindeno[1,2-b]pyrroles and Indeno[2′,1′:4,5]pyrrolo[1,2-a]-Fused 1,3-Diazaheterocycles

Abdolali Alizadeh*, Ameneh Zarei, Atieh Rezvanian
Department of Chemistry, Tarbiat Modares University, P. O. Box 14115-175, Tehran, Iran
Fax: +98(21)88006544; e-Mail: abdol_alizad@yahoo.com; e-Mail: aalizadeh@modares.ac.ir;

Abstract

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Abstract

An easy, highly efficient, and simple one-pot approach for the synthesis of dihyroindeno[1,2-b]pyrroles and indeno[2′,1′:4,5]pyrrolo[1,2-a]-fused 1,3-diazaheterocycles under mild conditions is reported. The reaction of a primary amine or 1,n-diamine with 1,1-bis(methylthio)-2-nitroethene in the presence of ninhydrin in aqueous media afforded the title compounds in good yields.

Key words

1,1-bis(methylthio)-2-nitroethene - ninhydrin - indeno[1,2-b]pyrrole - multicomponent reaction

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References

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