Endoscopy 2011; 43: E342
DOI: 10.1055/s-0030-1256795
Unusual cases and technical notes

© Georg Thieme Verlag KG Stuttgart · New York

A case of gastric ischemic necrosis

I.  S.  Papanikolaou1 , P.  G.  Foukas2 , A.  Sioulas1 , I.  Beintaris1 , P.  Panagopoulos3 , G.  Karamanolis1 , I.  G.  Panayiotides2 , G.  Dimitriadis1 , K.  Triantafyllou1
  • 1Hepatogastroenterology Unit, 2nd Department of Internal Medicine, Attikon University General Hospital, Medical School, Athens University, Greece
  • 22nd Department of Pathology, Attikon University General Hospital, Medical School, Athens University, Greece
  • 34th Department of Internal Medicine, Attikon University General Hospital, Medical School, Athens University, Greece
Further Information

I. S. PapanikolaouMD 

Attikon University General Hospital Medical School, Athens University

31 Vournazou Street
11521 Athens
Greece

Fax: +30-210-5326422

Email: ispapn@hotmail.com

Publication History

Publication Date:
21 October 2011 (online)

Table of Contents

Gastric ischemic necrosis (GIN) is a rare condition, usually seen postoperatively or after therapeutic embolizations [1]; in the absence of such surgical interventions, diagnosis can be delayed, a delay that can be fatal [2]. Patients are treated conservatively unless signs of perforation or sepsis develop,in which casegastrectomy is warranted [3].

We report a case of GIN in a patient without prior surgical or other invasive interventions. A 78-year-old man with a history of diabetes mellitus, hypertension, and atrial fibrillation presented with coffee-ground emesis and epigastric pain. He was in severe distress with a heart rate of 82 beats per minute, arterial blood pressure of 90/50 mm Hg, and a respiratory rate of 20 breaths per minute. His abdomen was tender with involuntary guarding and decreased bowel sounds. Pathological tests included an increased white blood cell (WBC) count (11 950/mm3), decreased hemoglobin (10.6 g/dL), elevated blood urea nitrogen (59.8 mg/dL), and hypoalbuminemia (2.7 g/dL). Radiographs showed no subdiaphragmatic free air. Abdominal computed tomography (CT) revealed thickened gastric folds; the major abdominal vessels had atherosclerotic lesions but no occlusion. Esophagogastroduodenoscopy revealed a hemorrhagic–ulcerative lesion of the major curvature ([Fig. 1]).

Zoom Image

Fig. 1 Upper-gastrointestinal endoscopy. a, b A hemorrhagic-ulcerative lesion which involves almost the entire major curvature of the stomach. Note the dark gastric mucosa with hemorrhagic and necrotic tissue due to ischemia. c, d The cardia and the antrum are unaffected.

Biopsies showed granulomatous interstitial nephritis (GIN) ([Fig. 2]).

Zoom Image

Fig. 2 An overview of the necrotic gastric mucosa, with infarction-like features. (Hematoxylin and eosin stain; original magnification × 4.)

The patient was treated with intravenous fluids and broad-spectrum antibiotics and was discharged after 12 days in good condition.

This case highlights a challenging entity,GIN, suggesting the importance of endoscopy in its prompt diagnosis.Although the patient had risk factors for gastric hypoperfusion (diabetes, hypertension, atrial fibrillation), he reported no abdominal interventions, and CT scans showed no vascular thrombosis or occlusion (although atherosclerosis and hypotension were probably responsible). This drew differential diagnosis away from GIN until endoscopy provided the diagnosis.

Endoscopy_UCTN_Code_CCL_1AB_2AD_3AF

Competing interests: None

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References

  • 1 Quentin V, Dib N, Thouveny F et al. Chronic ischemic gastritis: case report of a difficult diagnosis and review of the literature.  Endoscopy. 2006;  38 529-532
  • 2 Richieri J P, Pol B, Payan M J. Acute necrotizing ischemic gastritis: clinical, endoscopic and histopathologic aspects.  Gastrointest Endosc. 1998;  48 210-212
  • 3 Zerbib P, Voisin B, Truant S et al. The conservative management of severe caustic gastric injuries.  Ann Surg. 2011;  253 684-688

I. S. PapanikolaouMD 

Attikon University General Hospital Medical School, Athens University

31 Vournazou Street
11521 Athens
Greece

Fax: +30-210-5326422

Email: ispapn@hotmail.com

#

References

  • 1 Quentin V, Dib N, Thouveny F et al. Chronic ischemic gastritis: case report of a difficult diagnosis and review of the literature.  Endoscopy. 2006;  38 529-532
  • 2 Richieri J P, Pol B, Payan M J. Acute necrotizing ischemic gastritis: clinical, endoscopic and histopathologic aspects.  Gastrointest Endosc. 1998;  48 210-212
  • 3 Zerbib P, Voisin B, Truant S et al. The conservative management of severe caustic gastric injuries.  Ann Surg. 2011;  253 684-688

I. S. PapanikolaouMD 

Attikon University General Hospital Medical School, Athens University

31 Vournazou Street
11521 Athens
Greece

Fax: +30-210-5326422

Email: ispapn@hotmail.com

Zoom Image

Fig. 1 Upper-gastrointestinal endoscopy. a, b A hemorrhagic-ulcerative lesion which involves almost the entire major curvature of the stomach. Note the dark gastric mucosa with hemorrhagic and necrotic tissue due to ischemia. c, d The cardia and the antrum are unaffected.

Zoom Image

Fig. 2 An overview of the necrotic gastric mucosa, with infarction-like features. (Hematoxylin and eosin stain; original magnification × 4.)