Pulmonary Epithelioid Hemangioendothelioma with PlGF Expression: Report of a Case

Abstract

Pulmonary epithelioid hemangioendothelioma (PEH) is a relatively uncommon neoplasm of vascular origin with a low or intermediate grade of malignancy. We present a case of a 28-year-old female with multiple pulmonary nodules which were diagnosed as PEH by video-assisted thoracoscopic surgery (VATS) biopsy. In addition, we performed an immunohistochemical analysis for placenta growth factor (PlGF) and a strong positivity for PlGF observed, suggesting that the PlGF may play some role in the tumorigenesis of PEH.

Key words

Thoracic surgery - pulmonary epithelioid hemangioendothelioma (PEH) - video‐assisted thoracoscopic surgery (VATS) - placenta growth factor (PlGF) - vascular endothelial growth factor (VEGF)

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