Zusammenfassung
Die Blattdroge von Agathosma betulina (Rutaceae) wird seit Langem von verschiedenen Eingeborenenstämmen in Südafrika als
traditionelle Medizin zur Behandlung von Nieren- und Blasenerkrankungen, zur Entwässerung
des Körpers und zur Behandlung von Entzündungen verwendet. Wichtigster Inhaltsstoff
dieser Arzneipflanze ist das ätherische Öl, das durch Wasserdampfdestillation gewonnen
wird und als Cassis-Aroma bekannt ist, mit einem hohen Anteil an Monoterpenen, wobei
Monoterpen-Kohlenwasserstoffe und -Ketone mengenmäßig vorherrschen. Zusätzlich sind
Flavonoide isoliert worden. Neuere pharmakologische Untersuchungen konnten antioxidative,
schwache antimikrobielle sowie antiinflammatorische Wirkungen in vitro belegen. Bestimmte
Blattextrakte zeigten in vitro pro-oxidative Aktivitäten und führten zu DNA-Schädigungen.
Summary
Agathosma betulina (Berg.) Pillans – wild buchu
The leaves of Agathosma betulina (Rutaceae) have been used for a long time by indigenous South Africans as a traditional
remedy for the treatment of kidney- and bladder-disorders, fluid retention and inflammations.
The essential oil, prepared by steam distillation of the leaves and known as “Cassis
flavour”, consists of a high proportion of monoterpenes, especially monoterpenoid
hydrocarbons and ketones. Beside the essential oil, flavonoids have been isolated
from the leaves. Recent pharmacological studies demonstrate antioxidative, weak antimicrobial
and also anti-inflammatory effects in vitro. First toxicological in vitro studies
show DNA damages and pro-oxidative effects for certain leaf extracts.
Schlüsselwörter
Agathosma betulina
-
Barosma betulina
- Rutaceae - Buccostrauch - ätherisches Öl - antioxidativ - antiinflammatorisch -
Cassis-Aroma
Key words
Agathosma betulina
-
Barosma betulina
- Rutaceae - essential oil - buchu - antioxidative - anti-inflammatory effect - Cassis
flavour
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Dr. Klaus Peter Latté
Warägerweg 21
13595 Berlin
Email: latte@zedat.fu-berlin.de
Online
http://dx.doi.org/10.1055/s-0030-1247663
