New Fillers under Consideration: What Is the Future of Injectable Aesthetics?

ABSTRACT

The past 5 years in the United States have seen an explosion in the popularity of noninvasive aesthetic procedures. Not only have fillers and Botox turned out to be fantastically reliable and effective aesthetic tools, but also they have vastly expanded the accessibility of cosmetic procedures. Our cosmetic filler options are growing quickly as more and more fillers are coming before the U.S. Food and Drug Administration (FDA), seeking entry into the lucrative U.S. market. This article outlines the approval process that foreign fillers go through in their home countries and gives an idea of the fillers that are currently under consideration by the FDA. As our armamentarium of injectable fillers grows, it will be essential to know each product's strengths and weaknesses so that we can provide our patients with the best possible aesthetic results.

KEYWORDS

Injectable - filler - medical device - FDA - CE mark - hyaluronic acid - collagen - polyacrylamide - Aquamid - Atlèan - Novielle - Voluma - Juvéderm - Evolence - Prevelle - Belotero - Varioderm - Amalian - Teosyal

REFERENCES

• 1 Danish Medical Devices Certification Web site. Available at: http://dgm-nb.org/veje_til_ce/diagram-4.html Accessed 2/10/2009
• 2 Lemperle G. Injectable dermal fillers: resorbable or permanent? In: Aesthetic Surgery of the Facial Mosaic. Berlin, Germany; Springer 73: 650-664
• 3 Mazzoleni F, Dominici C, Lotti T et al.. Formacryl: un nuovo biopolimero al servizio della medicina piu un endoprotesi che un filler.  Dermatologia. 2000;  1 13
• 4 Karim R B, Hage J J, van Rozelaar L, Lange C A, Raaijmakers J. Complications of polyalkylimide 4% injections (Bio-Alcamid): a report of 18 cases.  J Plast Reconstr Aesthet Surg. 2006;  59 1409-1414
• 5 Raspaldo H. Volumizing effect of a new hyaluronic acid sub-dermal facial filler: a retrospective analysis based on 102 cases.  J Cosmet Laser Ther. 2008;  10 134-142
• 6 Wahl G. European evaluation of a new hyaluronic acid filler incorporating lidocaine.  J Cosmet Dermatol. 2008;  7 298-303