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Synfacts 2010(3): 0368-0368  
DOI: 10.1055/s-0029-1219286
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

C-S Cross-Coupling with Palladium on Charcoal

Contributor(s): Yasuhiro Uozumi, Tsubasa Muto
Z. Jiang, J. She, X. Lin*
Zhejiang University, Hangzhou, P. R. of China
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Publication History

Publication Date:
18 February 2010 (online)

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Significance

Palladium on charcoal (Pd/C) catalyzed the C-S cross-coupling reaction of thiols 1 with aryl halides 2 in the presence of potassium hydroxide to give the corresponding products 3 in up to 99% yield (14 examples).