Diastereoselective Domino Heck-Suzuki Reactions

doi:10.1055/s-0029-1217155

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Synfacts 2009(6): 0628-0628
DOI: 10.1055/s-0029-1217155

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

Diastereoselective Domino Heck-Suzuki Reactions

Contributor(s): Mark Lautens, Praew Thansandote
M. Braun*, B. Richrath
Universität Düsseldorf, Germany

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Publication History

Publication Date:
25 May 2009 (online)

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Significance

The authors describe a diastereoselective domino Heck-Suzuki reaction for the formation of trans-methylenetetrahydrofurans. The yields are moderate to low, although the diastereoselectivities are good to excellent.