Assessment of Left Ventricular Function Parameters with a New Three-Dimensional Shape Model

Zusammenfassung

Ziel: Untersuchung eines 3 D-Oberflächenmodells des linken Ventrikels (LV), welches die Berechnung von LV-Funktionsparametern anhand kurzer (KA) und langer Achsen (LA) ermöglicht. Vergleich mit herkömmlicher Simpson-Methode bei gesunden Probanden und in einem Patientenkollektiv. Material und Methoden: Cine-Bildgebung erfolgte mit einer prospektiv getriggerten SSFP-Sequenz: trueFISP: TR 3,6 ms, TE 1,8 ms, bFFE: TR 3,0 ms, TE 1,4 ms, Flipwinkel 60°, Auflösung 1,37 × 1,37 mm, Schichtdicke 8 mm, Schichtabstand 2 mm in KA-Orientierung von Apex bis Basis sowie in radialer LA-Orientierung (Rotationswinkel 15°) bei 11 gesunden Probanden und 27 Patienten mit Mitralklappeninsuffizienz. Das 3 D-Modell wurde an die manuell segmentierten Konturen angepasst. Fünf unterschiedliche Volumenberechnungsmethoden wurden verglichen: Simpson-Methode basierend auf alle KA (M0), 3 D-Oberflächenmodell basierend auf alle KA (M1a), 3 D-Oberflächenmodell basierend auf 3 KA (M1b), 3 D-Oberflächenmodell basierend auf alle KA und LA (M2a) und 3 D-Oberflächenmodell basierend auf 3 KA und 1 LA (M2b). Ergebnisse: M 0 und M 1a ergeben vergleichbare Ergebnisse (r: 0,99, b: 0,98). M 2a resultiert in größeren Volumina als M 0 aufgrund der Einbeziehung der LA-Konturen (b: 0,85). M 1b erzielt vergleichbare Volumina wie M 0 (r: 0,99, b: 1,02). M 2b erzielt vergleichbare Volumina wie M 2a (r: 0,99, b: 0,94). M 2b und M 0 ergeben vergleichbare Ergebnisse in dem Patientenkollektiv (r: 0,99, b: 0,97). Schlussfolgerung: Das vorgestellte 3D-Oberflächenmodell ermöglicht die Berücksichtigung von Konturinformationen, welche in unterschiedlichen Ebenen akquiriert wurden und deckt den linken Ventrikel durch Kombination von KA und LA genauer ab. Selbst mit einer reduzierten Anzahl segmentierter Konturen kann eine ausreichend genaue Oberflächenanpassung erfolgen.

Abstract

Purpose: To evaluate a 3D model of the left ventricle (LV) which allows calculation of LV function parameters on the basis of both short axis (SA) and long axis (LA) cine acquisitions. Comparison with the conventional Simpson’s rule method in a volunteer and patient collective. Materials and Methods: Cine imaging was performed with a prospectively triggered SSFP sequence: trueFISP: TR 3.6 msec, TE 1.8 msec, bFFE: TR 3.0 msec, TE 1.4 msec, flip angle 60°, resolution 1.37 × 1.37 mm, slice thickness 8 mm, gap 2 mm in SA orientation from apex to basis and in radial LA orientation (spacing 15°) in 11 volunteers and 27 patients with mitral valve insufficiency. Five different volume computations were compared: Simpson’s rule based on all SA slices (M0), 3D shape model based on all SA slices (M1a), 3D shape model based on 3 SA slices (M1b), 3D shape model based on all SA and LA slices (M2a), and 3D shape model based on 3 SA slices and 1 LA slice (M2b). Results: M 0 and M 1a give similar results (r: 0.99, b: 0.98). M 2a produces larger volumes than M 0 (b: 0.85) due to the inclusion of the LA contours. M 1b effectively reproduces the volumes computed with M 0 (r: 0.99, b: 1.02). M 2b effectively reproduces the volumes computed with M 2a (r: 0.99, b: 0.94). M 2b and M 0 give similar results in the patient collective (r: 0.99, b: 0.97). Conclusion: The proposed 3D shape model allows merging of information acquired in different orientations and thus the combination of SA and LA contours with better coverage of the left ventricle. It provides a suitable fit with a reduced number of segmented contours.

cardiac - anatomy - MR imaging

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