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Synfacts 2009(4): 0385-0385  
DOI: 10.1055/s-0028-1087837
Synthesis of Materials and Unnatural Products
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of Near-Infrared Emitting Naphthalimide Dyes

Contributor(s): Timothy M. Swager, Mindy Levine
L. Duan, Y. Xu, X. Qian*, Y. Zhang, Y. Liu
East China University of Science and Technology, Shanghai, P. R. of China
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Publication Date:
23 March 2009 (online)

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Significance

Near-infrared (NIR) emitting dyes are of interest for biological applications, as most biological analytes neither absorb nor fluoresce in that region, leading to greater sensitivity. The authors report the synthesis of two novel NIR dyes based on an interesting photochemical cyclization of naphthalimide derivatives, and the use of one of the dyes in imaging Chinese hamster cells.