Synthesis of (-)-Corilagin

doi:10.1055/s-0028-1087229

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Synfacts 2009(1): 0005-0005
DOI: 10.1055/s-0028-1087229

Synthesis of Natural Products and Potential Drugs

Synthesis of (-)-Corilagin

Contributor(s): Philip Kocienski, Stewart Eccles
H. Yamada*, K. Nagao, K. Dokei, Y. Kasai, N. Michihata
Kwansei Gakuin University, Sanda, Japan

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Publication History

Publication Date:
18 December 2008 (online)

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Significance

Corilagin was isolated from the tree Caesalpina coriaria and exhibits a range of biological activities such as the potentiation of β-lactam antibiotics against MRSA and antihypertensive effects. This paper reports the first synthesis of a ^¹C₄/B-ellagitannins.