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Synfacts 2008(11): 1228-1228  
DOI: 10.1055/s-0028-1083399
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Microwave-Based Heck Reaction with Palladium Nanoparticles

Contributor(s): Yasuhiro Uozumi, Yoshinori Hirai
S. Niembro, A. Shafir, A. Vallribera*, R. Alibes
Universitat Autonoma de Barcelona, Spain
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Publication History

Publication Date:
23 October 2008 (online)

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Significance

Palladium nanoparticles supported on an organic-inorganic hybrid material 2 bearing fluorous alkyl groups were prepared by treatment of Na2PdCl6 with 2 in the presence of NaOAc. The Heck reaction of iodobenzene and butyl acrylate was catalyzed by 2 mol% Pd of 3 to give butyl cinnamate in >99% conversion. The use of microwave shortened the reaction time from 24 hours to 1.5 hours.