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Klin Monbl Augenheilkd
DOI: 10.1055/a-2772-9058
DOI: 10.1055/a-2772-9058
Der interessante Fall
Visual Recovery after Intravenous Thrombolysis in Branch Retinal Artery Occlusion with Paracentral Defect: A Case Report
Visuelle Rückbildung nach intravenöser Thrombolyse bei retinalen Arterienastverschluss mit parazentralem Defekt: ein FallberichtAuthors
Introduction
Branch retinal artery occlusion (BRAO) is typically not considered an indication for systemic thrombolysis. However, in selected cases with relevant central or paracentral visual field loss, early reperfusion with intravenous thrombolysis (IVT) may be beneficial [1]. Evidence remains limited, and no standardized treatment exists. While (IVT) has shown promise in central retinal artery occlusion (CRAO) [2], [3], [4], its role in BRAO remains under investigation.
Publication History
Received: 31 October 2025
Accepted: 15 December 2025
Article published online:
11 February 2026
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References
- 1 Xie L, Zhang H, Ye X. et al. Intravenous Thrombolysis in Acute Branch Retinal Artery Occlusion Based on the Stroke Green Channel: A Case Report. J Med – Clin Res & Rev 2021; 5: 1-4
- 2 Huang L, Wang Y, Zhang R. Intravenous thrombolysis in patients with central retinal artery occlusion: a systematic review and meta-analysis. J Neurol 2022; 269: 1825-1833
- 3 Schrag M, Youn T, Schindler J. et al. Intravenous Fibrinolytic Therapy in Central Retinal Artery Occlusion: A Patient-Level Meta-analysis. JAMA Neurol 2015; 72: 1148-1154
- 4 Mac Grory B, Nackenoff A, Poli S. et al. Intravenous Fibrinolysis for Central Retinal Artery Occlusion: A Cohort Study and Updated Patient-Level Meta-Analysis. Stroke 2020; 51: 2018-2025
- 5 Schumacher M, Schmidt D, Jurklies B. et al. Central retinal artery occlusion: local intra-arterial fibrinolysis versus conservative treatment, a multicenter randomized trial. Ophthalmology 2010; 117: 1367-1375.e1
- 6 Helenius J, Arsava EM, Goldstein JN. et al. Concurrent acute brain infarcts in patients with monocular visual loss. Ann Neurol 2012; 72: 286-293
- 7 Fallico M, Lotery AJ, Longo A. et al. Risk of acute stroke in patients with retinal artery occlusion: a systematic review and meta-analysis. Eye (Lond) 2020; 34: 683-689
- 8 Ayrignac X, Zagroun C, Coget A. et al. Acute retinal arterial ischaemia: silent brain infarcts prevalence and short-term recurrence. Eur J Neurol 2020; 27: 2517-2522
- 9 Roskal-Wałek J, Mackiewicz J, Wałek P. et al. Long-term mortality after retinal artery occlusion – a single centre study. Ann Agric Environ Med 2023; 30: 252-258
- 10 Wai KM, Knapp A, Ludwig CA. et al. Risk of Stroke, Myocardial Infarction, and Death After Retinal Artery Occlusion. JAMA Ophthalmol 2023; 141: 1110-1116
