Genetics and Social Determinants of Health as Drivers of Epidemiologic Variation in Sarcoidosis

John Odackal; Elliott D. Crouser; Michelle Sharp; Yvette C. Cozier

doi:10.1055/a-2724-5501

Seminars in Respiratory and Critical Care Medicine, Table of Contents

Semin Respir Crit Care Med
DOI: 10.1055/a-2724-5501

Review Article

Genetics and Social Determinants of Health as Drivers of Epidemiologic Variation in Sarcoidosis

Authors

John Odackal

¹Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Davis Heart and Lung Institute, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio
Elliott D. Crouser

¹Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Davis Heart and Lung Institute, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio
Michelle Sharp

²Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland
Yvette C. Cozier

³Department of Epidemiology, Boston University School of Public Health, Slone Epidemiology Center at Boston University, Boston, Massachusetts

Abstract

Sarcoidosis is a disease with high morbidity that has variable epidemiology based on genetics and sociodemographic factors. The etiology of this variability remains incompletely understood. This narrative review describes how genetics, social determinants of health, and the interactions between them may contribute to the differences in epidemiology and health outcomes observed in different patient groups with sarcoidosis.

Keywords

sarcoidosis - epidemiology - social determinants of health - genetics - pulmonary medicine - health disparities

Full Text

References

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