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DOI: 10.1055/a-2584-1271
A modified variable flip angle release device for endoscopic titanium clips
Gefördert durch: Xiamen High-quality Development Medical Innovation Fund 2024GZL-CX58
Titanium clips are widely used in gastrointestinal endoscopy, especially during endoscopic surgical procedures. Their principal role is to efficiently close defects within the gastrointestinal tract, thereby mitigating the risk of postoperative complications [1] [2] [3] [4]. During clinical procedures, the alignment of the endoscope with the gastrointestinal lumen, coupled with the ongoing peristaltic movements of the stomach and intestinal cavities, frequently leads to suboptimal angulation for conventional titanium clip applicators when deploying clips via the endoscopeʼs channel, impeding the precise release of clips. Furthermore, the restricted opening angle of traditional titanium clips complicates their accurate placement on the wound surface, presenting considerable operational challenges.
Considering this, we have developed an innovative adjustable-angle endoscopic titanium clip release device. This device is composed of a clamp head assembly, a spring tube, a handle assembly, and an angle adjustment mechanism ([Fig. 1]). The clamp head assembly is welded to the spring tube, while the angle adjustment mechanism incorporates a side-pulling steel wire and an end pull ring, which is also welded to the tail of the titanium clip. In its static configuration, the side-pulling steel wire remains linear. Upon activation of the pull ring at the terminus of the angle adjustment mechanism, the side-pulling steel wire contracts, reducing the distance between the titanium clip and the junction of the spring tube and handle assembly, thereby bending the titanium clip to the desired angle ([Fig. 2]). The titanium clip is comprised of a tail end and a clip section. The tail end provides leverage during deployment to facilitate smooth clamping. The fully extended length of the titanium clip is approximately 10–15 mm, with an opening angle range of 90–135° ([Video 1]).




In summary, this modified variable-angle titanium clip-release device adapts to wounds throughout the digestive tract for more precise treatment.
Endoscopy_UCTN_Code_TTT_1AO_2AD
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Conflict of Interest
The authors declare that they have no conflict of interest.
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References
- 1 Qin G, Wang QQ, Tan C. A novel method for efficient closure of large mucosal defects using nylon loops combined with titanium clips after endoscopic submucosal dissection. Endoscopy 2023; 55 (Suppl. 01) E848-E849
- 2 Mou H, Liu Q, Fan Y. et al. Nylon ring with titanium clip assists endoscopic cyanoacrylate injection for the treatment of GOV1-type gastric varices. Endoscopy 2023; 55 (Suppl. 01) E578-E580
- 3 Yu J, Zhou CJ, Wang P. et al. Endoscopic titanium clip closure of gastric fistula after splenectomy: A case report. World J Clin Cases 2018; 6: 1047-1052
- 4 Zhan X, Wang B, Di D. et al. Endoscopic closure of gastric tube perforations with titanium clips: a four-case report. World J Surg Oncol 2015; 13: 25
Correspondence
Publikationsverlauf
Artikel online veröffentlicht:
09. Mai 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/).
Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany
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References
- 1 Qin G, Wang QQ, Tan C. A novel method for efficient closure of large mucosal defects using nylon loops combined with titanium clips after endoscopic submucosal dissection. Endoscopy 2023; 55 (Suppl. 01) E848-E849
- 2 Mou H, Liu Q, Fan Y. et al. Nylon ring with titanium clip assists endoscopic cyanoacrylate injection for the treatment of GOV1-type gastric varices. Endoscopy 2023; 55 (Suppl. 01) E578-E580
- 3 Yu J, Zhou CJ, Wang P. et al. Endoscopic titanium clip closure of gastric fistula after splenectomy: A case report. World J Clin Cases 2018; 6: 1047-1052
- 4 Zhan X, Wang B, Di D. et al. Endoscopic closure of gastric tube perforations with titanium clips: a four-case report. World J Surg Oncol 2015; 13: 25



