Synthetische Cannabinoide: eine narrative Übersicht

Zusammenfassung

Die seit einigen Jahren verfügbaren synthetischen Cannabinoiden (SC) zählen zu den NPS (neue psychoaktive Substanzen). Bei SC handelt es sich um eine sehr heterogene Gruppe von Substanzen mit häufig stark agonistischer Wirkung auf Cannabisrezeptoren, die beim Konsum vielfältige, zum Teil gesundheitsgefährdende Wirkungen auslösen können. Die SC gelten als die am häufigsten konsumierten NPS. Ziel dieser narrativen Übersicht ist es, aktuelle Kenntnisse hinsichtlich Pharmakologie, Epidemiologie, Wirkungen, Diagnostik und Risiko von Konsumstörungen sowie Behandlungsansätzen darzustellen.

Abstract

Synthetic cannabinoids (SC), which have been available for several years, are classified as NPS (new psychoactive substances). SC represent a highly heterogeneous group of substances that, when consumed, elicit a variety of effects, some of which pose significant health risks. SC are considered the most frequently consumed NPS. The aim of this narrative review is to present current knowledge regarding the pharmacology, epidemiology, effects, diagnostics, and risks of substance use disorders, as well as treatment approaches.

Schlüsselwörter

Neue pychoaktive Substanzen - Synthetische Cannabinoide - Cannabisrezeptor Agonisten - Epidemiologie - Klinische Wirkungen

Keywords

new psychoaktive substances - synthetic cannabinoids - cannabis receptor agonists - epidemiology - clinical effects

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