Nuklearmedizin 2025; 64(03): 228-230
DOI: 10.1055/a-2543-0846
Case Report

A Case of Male Breast Cancer Detected by Myocardial Perfusion Scintigraphy

Ahmet Eren Şen
1   Department of Nuclear Medicine, Konya City Hospital, Konya, Turkey (Ringgold ID: RIN591703)
,
Fatma Hicret Tekin
2   Department of Pathology, Konya City Hospital, Konya, Turkey (Ringgold ID: RIN591703)
,
Mustafa Erol
1   Department of Nuclear Medicine, Konya City Hospital, Konya, Turkey (Ringgold ID: RIN591703)
,
Ülkünur Çimen Şen
3   Department of Pathology, Necmettin Erbakan University Meram Medical Faculty Hospital, Konya, Turkey (Ringgold ID: RIN64222)
› Author Affiliations
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Introduction

Technetium-99m methoxyisobutyl isonitrile (Tc-99m MIBI) is widely used in myocardial perfusion scintigraphy (MPS) and parathyroid scintigraphy (PS). Tc-99m MIBI is also known to accumulate in malignant tissues, particularly in breast cancer. Here, we present a male patient who underwent MPS imaging and was subsequently diagnosed with breast cancer thanks to focal radiotracer uptake observed in the breast region. Additionally, we briefly discuss male breast cancer in the context of this case. To the best of our knowledge, no prior cases of male breast cancer diagnosed through MPS have been reported in the literature.



Publication History

Received: 02 November 2024

Accepted after revision: 19 February 2025

Article published online:
12 March 2025

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  • References

  • 1 Ionescu S, Nicolescu AC, Marincas M. et al. An Update on the General Features of Breast Cancer in Male Patients-A Literature Review. Diagnostics (Basel) 2022; 12 (07) 1554
  • 2 Abdelwahab Yousef AJ. Male Breast Cancer: Epidemiology and Risk Factors. Semin Oncol 2017; 44 (04) 267-272
  • 3 AlFehaid M. Male Breast Cancer (MBC) – A Review. Pol Przegl Chir 2023; 95 (06) 24-30
  • 4 Fentiman I. Male breast cancer: a review. Ecancermedicalscience 2009; 3: 140
  • 5 Fentiman IS. Surgical options for male breast cancer. Breast Cancer Res Treat 2018; 172: 539-544
  • 6 Lin AP, Huang TW, Tam KW. Treatment of male breast cancer: meta-analysis of real-world evidence. Br J Surg 2021; 108 (09) 1034-1042
  • 7 Yalaza M, İnan A, Bozer M. Male Breast Cancer. J Breast Health 2016; 12 (01) 1-8
  • 8 Hassett MJ, Somerfield MR, Baker ER. et al. Management of male breast cancer: ASCO guideline. J Clin Oncol 2020; 38: 1849-1863
  • 9 Khan MH, Allerton R, Pettit L. Hormone therapy for breast cancer in men. Clin Breast Cancer 2015; 15: 245-250
  • 10 Moadel RM. Breast cancer imaging devices. Semin Nucl Med 2011; 41: 229-241
  • 11 Khalkhali I, Villanueva-Meyer J, Edell SL. et al. Diagnostic accuracy of 99mTc-sestamibi breast imaging: multicenter trial results. J Nucl Med 2000; 41: 1973-1979
  • 12 Yoon HJ, Kim Y, Lee JE. et al. Background 99mTc-methoxyisobutylisonitrile uptake of breast-specific gamma imaging in relation to background parenchymal enhancement in magnetic resonance imaging. Eur Radiol 2015; 25: 32-40
  • 13 Fukumoto M. Single-photon agents for tumor imaging: 201Tl, 99mTc-MIBI, and 99mTc-tetrofosmin. Ann Nucl Med 2004; 18: 79-95
  • 14 Kim IJ, Bae YT, Kim SJ. et al. Determination and prediction of P-glycoprotein and multidrug-resistance-related protein expression in breast cancer with double-phase technetium-99m sestamibi scintimammography. Visual and quantitative analyses. Oncology 2006; 70: 403-410