RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000131.xml
PDF herunterladen
Synfacts 2025; 21(04): 365
DOI: 10.1055/a-2539-2952
DOI: 10.1055/a-2539-2952
Metals in Synthesis
Photoredox-Catalyzed Acylesterification of Alkenes Using Acyloxime Esters as Bifunctional Reagents
Zhou Y,
Zhao R,
Hu M,
Duan X-H,
Liu L *.
Xi’an Jiaotong University, P. R. China
Photoredox-Catalyzed Alkene Acylesterification with Acyloxime Esters via C–C and Tertiary C–O Bond Formation.
Org. Lett. 2025;
27: 623-628
DOI: 10.1021/acs.orglett.4c04422
Photoredox-Catalyzed Alkene Acylesterification with Acyloxime Esters via C–C and Tertiary C–O Bond Formation.
Org. Lett. 2025;
27: 623-628
DOI: 10.1021/acs.orglett.4c04422
Significance
Liu and co-workers developed a photoredox-catalyzed acylesterification of terminal alkenes using acyloximes as bifunctional group transfer reagents. This protocol features good functional group tolerance, affording synthetically valuable α-acyl hindered alcohol esters in good yields.
MissingLinkText
Comment
A mechanistic study supports the shown photoredox-catalyzed cycle, which follows a
radical polar crossover mechanism. The key to this transformation was the use of fac-Ir(ppy)3 as the photocatalyst.
MissingLinkText
MissingLinkText
Publikationsverlauf
Artikel online veröffentlicht:
25. März 2025
© 2025. Thieme. All rights reserved.
Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany