Challenging Cases in Neurology: Neurologic Complications of COVID-19

Abstract

Since the first reported cases of pneumonia in December 2019, coronavirus disease 2019 (COVID-19) has rapidly become recognized as a multisystem illness, with known effects on virtually every organ system. In particular, neurologic complications of COVID-19 have been reported since the beginning of the pandemic in both ambulatory patients with mild disease and critically ill patients. Although it remains unclear whether severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has the potential to directly invade the central nervous system, strokes and other neurovascular complications, sequelae of critical illness and metabolic derangements, parainfectious inflammatory disorders, and a poorly understood post-COVID syndrome have all been reported in patients with COVID-19. Here, we describe cases representing a diverse range of neurologic complications in patients infected with COVID-19.

Keywords

COVID-19 - encephalitis - GAD-65 encephalitis - osmotic demyelination syndrome - anterior biopercular syndrome

^* Equal contribution.

Publication History

Accepted Manuscript online:
23 November 2022

Article published online:
27 December 2022

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