Subscribe to RSS
DOI: 10.1055/a-1515-1517
Tätowierung durch intradermale Hauttests mit farbstoffhaltigen Medikamenten
Intradermal Skin Test-Induced Tattoos from Color-Containing Drugs
Zusammenfassung
Bei zwei Individuen, einem 72-jährigen Patienten und einer 20-jährigen Kontrollprobandin, wurde bei der Durchführung von Hauttests mit farbigen Medikamenten eine iatrogene Tätowierung verursacht. Der Patient hatte eine anaphylaktische Reaktion auf ein Eisenpräparat erlitten, und es bestand die zwingende Indikation für eine erneute intravenöse Eisensubstitution. Deshalb wurden weiterführende Abklärungen inklusive Hauttests durchgeführt. Die zweite Tätowierung erfolgte im Rahmen einer Studie zur Evaluation des irritativen Potenzials von Intradermaltests mit Isosulfanblau, einem diagnostischen Farbstoff. In beiden Fällen war vorab eine Einverständniserklärung bzw. ein Ethikvotum eingeholt worden, sodass es zu keinen weiteren rechtlichen Konsequenzen kam.
Abstract
In two individuals, a 72-year-old male patient and a 20-year-old female control subject, iatrogenic tattooing was caused through skin tests with colored drugs. The male patient had suffered an anaphylactic reaction to an iron preparation and there was a compelling indication for renewed intravenous iron supplementation. Therefore, further investigations including skin tests were performed. The second iatrogenic tattoo was performed as part of a study to evaluate the irritative potential of intradermal tests with isosulfane blue, a diagnostic dye. In both cases, a declaration of consent or ethical vote had been obtained in advance, therefore, there were no further legal consequences.
Publication History
Article published online:
15 February 2022
© 2022. Thieme. All rights reserved.
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
-
Literatur
- 1 Morales Mateluna CA, Scherer Hofmeier K, Bircher AJ. Approach to hypersensitivity reactions from intravenous iron preparations. Allergy 2017; 72: 827-830 DOI: 10.1111/all.13106.
- 2 Hempel J, Poppelaars F, Gaya da Costa M. et al. Distinct in vitro Complement Activation by Various Intravenous Iron Preparations. Am J Nephrol 2017; 45: 49-59 DOI: 10.1159/000451060.
- 3 Scherer K, Studer W, Figueiredo V. et al. Anaphylaxis to isosulfan blue and cross-reactivity to patent blue V: case report and review of the nomenclature of vital blue dyes. Ann Allergy Asthma Immunol 2006; 96: 497-500 DOI: 10.1016/S1081-1206(10)60921-0.
- 4 Barbaud A, Waton J. Systemic Allergy to Corticosteroids: Clinical Features and Cross Reactivity. Curr Pharm Des 2016; 22: 6825-6831 DOI: 10.2174/1381612822666161013092339.
- 5 Elsner P, Meyer J. Lipatrophie nach Triamcinolon-Injektion. Akt Dermatol 2020; 46: 551-553 DOI: 10.1055/a-1206-4391.
- 6 Castelain M. [Side effects, complications and contraindications of patch-tests]. Ann Dermatol Venereol 2009; 136: 645-649 DOI: 10.1016/j.annder.2009.06.010.
- 7 Lachapelle J-M, Maibach HI. Patch Testing and Prick Testing: A Practical Guide Official Publication of the ICDRG. 2nd ed. Berlin, Heidelberg: Springer; 2009. DOI: 10.1007/978-3-540-92806-5
- 8 Ludman S, Penagos M, Brough HA. et al. Postinflammatory Hyperpigmentation After Skin Prick Testing. WAO Journal 2012; DOI: 10.1097/WOX.0b013e3182488069: 57-58.
- 9 Hermitte-Gandoliere A, Petitpain N, Lepelley M. et al. [Cutaneous pigmentation related to intravenous iron extravasation: Analysis from the French pharmacovigilance database]. Therapie 2018; 73: 193-198 DOI: 10.1016/j.therap.2017.10.005.
- 10 Raulin C, Werner S, Greve B. Circumscripted pigmentations after iron injections-treatment with Q-switched laser systems. Lasers Surg Med 2001; 28: 456-460 DOI: 10.1002/lsm.1074.
- 11 Wong M, Bryson M. Extensive skin hyperpigmentation following intravenous iron infusion. Br J Haematol 2019; 184: 709 DOI: 10.1111/bjh.15628.
- 12 Thompson J, Pavord S, Lim K. Severe haemosiderin pigmentation after intravenous iron infusion. Intern Med J 2014; 44: 706-708 DOI: 10.1111/imj.12467.