Ernährung bei Brustkrebs im frühen Stadium

Zusammenfassung

Während der akuten Erkrankung sind starke Gewichtsabnahme und Mangelernährung bei Frauen mit Brustkrebs eher selten. Es besteht jedoch ein Risiko für eine Gewichtszunahme unter Chemotherapie, v. a. bei jüngeren Patientinnen, die vorzeitig in die Menopause versetzt wurden. Auch nach Abschluss der Therapie nehmen mehr als 50 % der überlebenden Frauen an Gewicht zu. Lebensstilmodifikation, Ernährungsumstellung und Bewegung können die Prognose verbessern.

Publication History

Article published online:
17 March 2021

• Literatur

• 1 Robert Koch-Institut (RKI). Brustkrebs (Mammakarzinom) ICD-10 C50, 2016. https://www.krebsdaten.de/Krebs/DE/Content/Krebsarten/Brustkrebs/brustkrebs_node.html Abruf am 01.02.2021
• 2 Leitlinienprogramm Onkologie der Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften e. V., der Deutschen Krebsgesellschaft e. V. und der Stiftung Deutsche Krebshilfe. Patientinnenleitlinie „Brustkrebs im frühen Stadium“ 2018. https://www.leitlinienprogramm-onkologie.de/fileadmin/user_upload/Downloads/Patientenleitlinien/Patientenleitlinie_Brustkrebs_im_fruehen_Stadium.pdf_v04–2020.pdf Abruf am 8.2.2021
• 3 Hebuterne X, Lemarie E, Michallet M. et al. Prevalence of malnutrition and current use of nutrition support in patients with cancer. J Parenteral Enteral Nutr 2014; 38: 196-204
• 4 Honecker F, Claßen J, Preiß J. et al., Hrsg. Taschenbuch Onkologie: Interdisziplinäre Empfehlungen zur Therapie 2018/2019. München: W. Zuckschwerdt; 2018
• 5 Schvartsman G, Gutierrez-Barrera AM, Song J. et al. Association between weight gain during adjuvant chemotherapy for early-stage breast cancer and survival outcomes. Cancer Med 2017; 6: 2515-2522
• 6 Demark-Wahnefried W, Campbell KL, Hayes SC. Weight management and its role in breast cancer rehabilitation. Cancer 2012; 118 (8 Suppl): 2277-2287
• 7 Nissen MJ, Shapiro A, Swenson KK. Changes in weight and body composition in women receiving chemotherapy for breast cancer. Clin Breast Cancer 2011; 11: 52-60
• 8 Kohlenberg-Müller K. Ernährungs-Leitlinien für „Cancer Surviors“–Wie gelingt Brustkrebsbetroffenen die Umsetzung?. Aktuel Ernahrungsmed 2015; 40: 335-340
• 9 Nichols HB, Trentham-Dietz A, Egan KM. et al. Body mass index before and after breast cancer diagnosis: associations with all-cause, breast cancer, and cardiovascular disease mortality. Cancer Epidemiol Biomarkers Prev 2009; 18: 1403-1409
• 10 Jiralerspong S, Goodwin PJ. Obesity and breast cancer prognosis: Evidence, challenges, and opportunities. J Clin Oncol 2016; 34: 4203-4216
• 11 Bao PP, Cai H, Peng P. et al. Body mass index and weight change in relation to triple-negative breast cancer survival. Cancer Causes Control 2016; 27: 229-236
• 12 Petru E, Petru C. Langzeitüberleben nach Brustkrebs. Berlin, Heidelberg: Springer; 2015
• 13 Chlebowski RT, Blackburn GL, Thomson CA. et al. Dietary fat reduction and breast cancer outcome: interim efficacy results from the Women’s Intervention Nutrition Study. J National Cancer Inst 2006; 98: 1767-1776
• 14 Chlebowski RT, Aragaki AK, Anderson GL. et al. Low-fat dietary pattern and breast cancer mortality in the Women’s Health Initiative Randomized Controlled Trial. J Clin Oncol 2017; 35: 2919-2926
• 15 Pierce JP, Natarajan L, Caan BJ. et al. Influence of a diet very high in vegetables, fruit, and fiber and low in fat on prognosis following treatment for breast cancer: the Women’s Healthy Eating and Living (WHEL) randomized trial. J Am Med Assoc 2007; 298: 289-298
• 16 Pierce JP. Diet and breast cancer prognosis: making sense of the Women’s Healthy Eating and Living and Women’s Intervention Nutrition Study trials. Curr Opin Obstet Gynecol 2009; 21: 86-91
• 17 Kwan ML, Weltzien E, Kushi LH. et al. Dietary patterns and breast cancer recurrence and survival among women with early-stage breast cancer. J Clin Oncol 2009; 27: 919-926
• 18 Vrieling A, Buck K, Seibold P. et al. Dietary patterns and survival in German postmenopausal breast cancer survivors. Br J Cancer 2013; 108: 188-192
• 19 Rack B, Andergassen U, Neugebauer J. et al. The German SUCCESS C Study – The First European Lifestyle Study on Breast Cancer. Breast Care (Basel) 2010; 5: 395-400
• 20 American Association for Cancer Research (AACR). Lifestyle intervention helped breast cancer survivors lose weight, and was associated with higher disease-free survival rates 2018. https://www.aacr.org/about-the-aacr/newsroom/news-releases/lifestyle-intervention-helped-breast-cancer-survivors-lose-weight-and-was-associated-with-higher-disease-free-survival-rates/ Abruf am 1.2.2021
• 21 World Cancer Research Found (WCRF). Diet, nutrition, physical actvity and breast cancer survivors revised 2018. https://www.wcrf.org/sites/default/files/Breast-cancer-survivors-report.pdf Abruf am 31.1.2021
• 22 American Institute for Cancer Research (AICR). “What breast cancer survivors can do” last updated on January 29, 2020. https://www.aicr.org/wp-content/uploads/2020/01/bcs-can-do.jpg Abruf am 31.1.2021
• 23 Messina M. Impact of soy foods on the development of breast cancer and the prognosis of breast cancer patients. Complement Med Res 2016; 23: 75-80
• 24 Messina M, Hilakivi-Clarke L. Early intake appears to be the key to the proposed protective effects of soy intake against breast cancer. Nutr Cancer 2009; 61: 792-798
• 25 Arbeitsgemeinschaft der Gynäkologischen Onkologie e. V. (AGO). BRUSTKREBS – Patientenratgeber zu den AGO Empfehlungen 2019. https://www.ago-online.de/fileadmin/ago-online/downloads/AGO_Brustkrebs_2019.pdf Abruf am 31.1.2021
• 26 Zhang FF, Haslam DE, Terry MB. et al. Dietary isoflavone intake and all-cause mortality in breast cancer survivors: The Breast Cancer Family Registry. Cancer 2017; 123: 2070-2079
• 27 Erickson N, Schaller N, Berling-Ernst AP. et al. Ernährungspraxis Onkologie. Stuttgart: Schattauer; 2017
• 28 Dorgan JF, Baer DJ, Albert PS. et al. Serum hormones and the alcohol-breast cancer association in postmenopausal women. J National Cancer Inst 2001; 93: 710-715
• 29 Ali AM, Schmidt MK, Bolla MK. et al. Alcohol consumption and survival after a breast cancer diagnosis: a literature-based meta-analysis and collaborative analysis of data for 29,239 cases. Cancer Epidemiol Biomarkers Prev 2014; 23: 934-945
• 30 Campbell KL, Winters-Stone KM, Wiskemann J. et al. Exercise Guidelines for Cancer Survivors: Consensus Statement from International Multidisciplinary Roundtable. Med Sci Sports Exerc 2019; 51: 2375-2390
• 31 Lahart IM, Metsios GS, Nevill AM. et al. Physical activity, risk of death, and recurrence in breast cancer survivors: A systematic review and meta-analysis of epidemiological studies. Acta Oncol 2015; 54: 635-654