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Klin Monbl Augenheilkd 2020; 237(04): 487-489
DOI: 10.1055/a-1112-6914
DOI: 10.1055/a-1112-6914
Der interessante Fall
Striking Funduscopic Findings in a Patient after Drug-Supported Sexual Activity
Auffällige Funduskopie bei einem Patienten nach medikamentös unterstützter sexueller AktivitätFurther Information
Publication History
received 24 September 2019
accepted 16 January 2020
Publication Date:
24 April 2020 (online)

Background
It has been described that an exhaustive Valsalva maneuver may lead to ocular pathologies. The Valsalva maneuver can occur, e.g., during sexual activity. Furthermore, sildenafil is one of the most commonly used drugs for management of sexual dysfunction or enhancement of sexual activity. While sildenafil is generally well tolerated, a plethora of rare ocular side effects have been associated with its use.
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References
- 1 Friberg TR, Braunstein RA, Bressler NM. Sudden visual loss associated with sexual activity. Arch Ophthalmol 1995; 113: 738-742 doi:10.1001/archopht.1995.01100060064033
- 2 Schwarz ER, Kapur V, Rodriguez J. et al. The effects of chronic phosphodiesterase-5 inhibitor use on different organ systems. Int J Impot Res 2007; 19: 139-148 doi:10.1038/sj.ijir.3901491
- 3 Achiron A, Hecht I, Juza C. et al. The effect of sildenafil on retinal blood velocity in healthy subjects. Eye Vis (Lond) 2018; 5: 30 doi:10.1186/s40662-018-0125-y
- 4 Sponsel WE, Paris G, Sandoval SS. et al. Sildenafil and ocular perfusion. N Engl J Med 2000; 342: 1680 doi:10.1056/NEJM200006013422218
- 5 Polak K, Wimpissinger B, Berisha F. et al. Effects of sildenafil on retinal blood flow and flicker-induced retinal vasodilatation in healthy subjects. Invest Ophthalmol Vis Sci 2003; 44: 4872-4876 doi:10.1167/iovs.03-0177
- 6 Grunwald JE, Metelitsina T, Grunwald L. Effect of sildenafil citrate (Viagra) on retinal blood vessel diameter. Am J Ophthalmol 2002; 133: 809-812 doi:10.1016/s0002-9394(02)01391-0
- 7 Eltony SA, Abdelhameed SY. Effect of chronic administration of sildenafil citrate (Viagra) on the histology of the retina and optic nerve of adult male rat. Tissue Cell 2017; 49: 323-335 doi:10.1016/j.tice.2017.01.006
- 8 Moschos MM, Nitoda E. Pathophysiology of visual disorders induced by phosphodiesterase inhibitors in the treatment of erectile dysfunction. Drug Des Devel Ther 2016; 8: 3407-3413 doi:10.2147/DDDT.S118015
- 9 Miguel A, Henriques F, Azevedo LF. et al. Ophthalmic adverse drug reactions to systemic drugs: a systematic review. Pharmacoepidemiol Drug Saf 2014; 23: 221-233 doi:10.1002/pds.3566
- 10 Simakurthy S, Tripathy K. Valsalva Retinopathy. In: StatPearls. Treasure Island, FL: StatPearls Publishing; 2019
- 11 Mukherjee C, Kumar A, Mitra A. Valsalva maculopathy: To treat or not to treat. Oman J Ophthalmol 2018; 11: 78-81 doi:10.4103/ojo.OJO_91_2016
- 12 Hussain RN, Stappler T, Hiscott P. et al. Histopathological Changes and Clinical Outcomes following Intervention for Sub-Internal Limiting Membrane Haemorrhage. Ophthalmologica 2019;
- 13 Kokame GT, Yamamoto I, Kishi S. et al. Intrapapillary hemorrhage with adjacent peripapillary subretinal hemorrhage. Ophthalmology 2004; 111: 926-930 doi:10.1016/j.ophtha.2003.08.040