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Nervenheilkunde 2019; 38(12): 929-935
DOI: 10.1055/a-0998-0264
Schwerpunkt
© Georg Thieme Verlag KG Stuttgart · New York

Schläfenlappenepilepsie

Neuropathologiespektrum revisitedTemporal lobe epilepsy
Pitt Niehusmann
1   Abteilung für Neuro-/Pathologie, Universitätsklinikum Oslo
,
Albert J. Becker∗
2   Sektion für Translationale Epilepsieforschung am Institut für Neuropathologie, Universitätsklinikum Bonn
› Author Affiliations
Further Information

Publication History

Publication Date:
17 December 2019 (online)

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ZUSAMMENFASSUNG

Die Schläfenlappenepilepsie stellt die häufigste fokale Epilepsieform dar. Trotz etablierter Pathologiemuster ergaben sich zuletzt grundlegende Innovationen im Hinblick sowohl auf erworbene Epilepsien mit hippocampalem Ursprung als auch bei fokalen kortikalen Dysplasien und epilepsieassoziierten, oft glioneuronalen Tumoren. Besondere Erwähnung finden Verbesserungen des molekulargenetischen Verständnisses der Erkrankungen.

ABSTRACT

Temporal lobe epilepsy represents the most frequent form of focal epilepsy. Despite established pathology patterns fundamental innovations concerning acquired epilepsies affecting the hippocampal formation as well as with respect to focal cortical dysplasias and epilepsy-associated, often glioneuronal tumors have emerged. Particular emphasis of this article will be on the improvement of the molecular-genetic understanding of these diseases.

Schlüsselwörter

Hippocampussklerose - Dysplasie - LEA-Tumor

Key words

Hippocampal sclerosis - dysplasia - LEA tumor
 

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