Zusammenfassung
Sterile Keratitiden können als rein okuläres Problem, aber auch im Rahmen einer potenziell
letalen Grunderkrankung auftreten. Diagnosestellung und Management dieser Erkrankung
sind eine große Herausforderung für den Augenarzt. Neben therapeutischen Grundprinzipien
für alle nicht infektiösen Keratitiden und Ulzerationen bestimmt die jeweilige Pathogenese
die spezifische, u. U. lebensrettende Behandlung. Daher muss vor jeder Therapie eine
akkurate, wegweisende Diagnose stehen.
Abstract
Sterile keratitis shows multiple manifestations. It may occur as an ophthalmological
problem but can also be part of a systemic disease, including potentially lethal systemic
vasculitis. Diagnosis as well as management of this disease is a challenging task
for the ophthalmologist. There are therapeutic principles which apply to all non-infectious
cases of keratitis and corneal ulcerations. Specific treatments, however, are determined
by the pathogenesis and may differ. Therefore, an accurate diagnosis must guide therapeutic
decision making. The correct diagnosis and management of sterile ulcerative keratitis
is able to restore the patientʼs vision in most cases. In potentially lethal systemic
disease it may even be able to save the patientʼs life.
Schlüsselwörter
periphere ulzerative Keratitis - okuläre Allergie - neurotrophe Keratopathie - interstitielle
Keratitis - diffuse lamelläre Keratitis
Key words
peripheral ulcerative keratitis - ocular allergy - neurotrophic keratopathy - interstitial
keratitis - diffuse lamellar keratitis