Abstract
Objective The aim of this study was to follow-up people with diabetes type 1 and Flash Glucose
Monitoring (FGM) regarding metabolic control and treatment satisfaction.
Methods 40 people with diabetes type 1 and FGM use of ≥6 months were included in the study
(female 55%, age 50.9 y, diabetes duration 21.9 y, HbA1c 7.4%, 57.6 mmol/mol, insulin
pump therapy 32.5%). The number of scans per day and time/frequency of hypoglycaemia
(interstitial glucose value ≤3.9 mmol/l) was recorded from 28 days of the glucose
readings. Change of treatment satisfaction was assessed with the DTSQc questionnaire
at follow-up (range−18 to+18).
Results Mean time of follow-up was 1.0±0.4 y. At follow-up, all participants scanned interstitial
glucose 11.9±7.7 times/day. Number of self-monitoring of blood glucose decreased from
6.7±4.2 (baseline) to 0.9±1.8 (follow-up) per day (p<0.001). In individuals with baseline
HbA1c ≤7.5%, HbA1c increased (from 6.6±0.7% to 7.0±0.4%, p=0.020). On the contrary,
in people with HbA1c>7.5%, HbA1c decreased (from 8.2±0.7% to 7.8±0.7%, p=0.001). In
all participants, there were no differences regarding insulin dosage (33.8±12.9 vs.
34.6±13.9 IU/day, p=0.679) and number of insulin injections/day (3.9±2.3 vs. 4.0±2.6,
p=0.813) between baseline and follow-up. Frequency of symptomatic hypoglycaemia was
at baseline 0.3±0.3 events/day and 0.48±0.36 events/day (recognised, symptomatic events)
at follow-up, respectively. In addition, 0.26±0.21 unrecognised hypoglycaemic events/day
occurred at follow-up. Treatment satisfaction increased by+12.6 points.
Conclusions FGM was associated with an enormous increase in treatment satisfaction and slightly
improved metabolic control in people with baseline HbA1c>7.5%. The number of capillary
glucose measurements decreased significantly.
Key words
flash glucose monitoring - type 1 diabetes - freestyle libre
