ZWR - Das Deutsche Zahnärzteblatt, Table of Contents ZWR - Das Deutsche Zahnärzteblatt 2018; 127(06): 276-283DOI: 10.1055/a-0622-5589 Fortbildung | Parodontologie Georg Thieme Verlag KG Stuttgart · New YorkDie Rolle der Ernährung in der Ätiologie parodontaler Erkrankungen Ulrich Schlagenhauf Recommend Article Abstract Buy Article Aus Untersuchungen ist seit Langem bekannt, dass das Ernährungsverhalten den Verlauf chronischer Entzündungen signifikant beeinflussen kann. Daher ist die Rolle der Ernährung bei der Entstehung parodontaler Erkrankungen mittlerweile auch in den Fokus zahnärztlicher Forschung gerückt. Was genau können entzündungsmodulierende Nahrungsbestandteile sowie diätische Aspekte zur Therapie und Prävention parodontaler Erkrankungen beitragen? Full Text References Literatur 1 Mozaffarian D. Dietary and policy priorities for cardiovascular disease, diabetes, and obesity: A comprehensive review. Circulation 2016; 133: 187-225 2 Stanhope KL. Sugar consumption, metabolic disease and obesity: The state of the controversy. Crit Rev Clin Lab Sci 2016; 53: 52-67 3 Keller A, Rohde JF, Raymond K. et al. Association between periodontal disease and overweight and obesity: A systematic review. J Periodontol 2015; 86: 766-776 4 Varela-López A, Giampieri F, Bullón P. et al. Role of lipids in the onset, progression and treatment of periodontal disease. A systematic review of studies in humans. Int J Mol Sci 2016; 5 Chapple IL. Potential mechanisms underpinning the nutritional modulation of periodontal inflammation. J Am Dent Assoc 2009; 140: 178-184 6 Muniz FW, Nogueira SB, Mendes FL. et al. The impact of antioxidant agents complimentary to periodontal therapy on oxidative stress and periodontal outcomes: A systematic review. Arch Oral Biol 2015; 60: 1203-1214 7 Flock MR, Rogers CJ, Prabhu KS. et al. Immunometabolic role of long-chain omega-3 fatty acids in obesity-induced inflammation. Diabetes Metab Res Rev 2013; 29: 431-445 8 Kesavalu L, Vasudevan B, Raghu B. et al. Omega-3 fatty acid effect on alveolar bone loss in rats. J Dent Res 2006; 85: 648-652 9 Khatri J, Mills CE, Maskell P. et al. It is rocket science – why dietary nitrate is hard to ‘beet’! Part I: twists and turns in the realization of the nitrate-nitrite-NO pathway. Br J Clin Pharmacol 2017; 83: 129-139 10 Mills CE, Khatri J, Maskell P. et al. It is rocket science – why dietary nitrate is hard to ‘beet’! Part II: further mechanisms and therapeutic potential of the nitrate-nitrite-NO pathway. Br J Clin Pharmacol 2017; 83: 140-151 11 Jockel-Schneider Y, Gossner SK, Petersen N. et al. Stimulation of the nitrate-nitrite-NO-metabolism by repeated lettuce juice consumption decreases gingival inflammation in periodontal recall patients: a randomized, double-blinded, placebo-controlled clinical trial. J Clin Periodontol 2016; 43: 603-608 12 Bryan NS, Alexander DD, Coughlin JR. Ingested nitrate and nitrite and stomach cancer risk: An updated review. Food Chem Toxicol 2012; 50: 3646-3665 13 Zaura E, Brandt BW, Prodan A. et al. On the ecosystemic network of saliva in healthy young adults. ISME J 2017; 11: 1218-1231 14 Mazmanian SK, Round JL, Kasper DL. A microbial symbiosis factor prevents intestinal inflammatory disease. Nature 2008; 453: 620-625 15 Alexander KL, Targan SR, Elson 3rd CO. Microbiota activation and regulation of innate and adaptive immunity. Immunol Rev 2014; 260: 206-220 16 Ganzle MG. Reutericyclin: biological activity, mode of action, and potential applications. Appl Microbiol Biotechnol 2014; 64: 326-332 17 Bene KP, Kavanaugh DW, Leclaire C. et al. Lactobacillus reuteri surface mucus adhesins upregulate inflammatory responses through interactions with innate c-type lectin receptors. Front Microbiol 2017; 8: 321 18 Saavedra JM, Abi-Hanna A, Moore N. et al. Long-term consumption of infant formulas containing live probiotic bacteria: tolerance and safety. Am J Clin Nutr 2004; 79: 261-267 19 Twetman S, Derawi B, Keller M. et al. Short-term effect of chewing gums containing probiotic lactobacillus reuteri on the levels of inflammatory mediators in gingival crevicular fluid. Acta Odontol Scand 2009; 67: 19-24 20 Schlagenhauf U, Jakob L, Eigenthaler M. et al. Regular consumption of Lactobacillus reuteri-containing lozenges reduces pregnancy gingivitis: an RCT. J Clin Periodontol 2016; 43: 948-954 21 Teughels W, Durukan A, Ozcelik O. et al. Clinical and microbiological effects of lactobacillus reuteri probiotics in the treatment of chronic periodontitis: A randomized placebo-controlled study. J Clin Periodontol 2013; 40: 1025-1035 22 Bondonno CP, Liu AH, Croft KD. et al. Antibacterial mouthwash blunts oral nitrate reduction and increases blood pressure in treated hypertensive men and women. Am J Hypertens 2015; 28: 572-575