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Homeopathy 2010; 99(04): 249-254
DOI: 10.1016/j.homp.2010.08.002
Original Paper
Copyright © The Faculty of Homeopathy 2010

Homeopathic Symphytum officinale increases removal torque and radiographic bone density around titanium implants in rats

Rubens Spin-Neto
1   UNESP – Univ Estadual Paulista, Araraquara Dental School, Department of Periodontology, Araraquara, São Paulo, Brazil
,
Marina Montosa Belluci
1   UNESP – Univ Estadual Paulista, Araraquara Dental School, Department of Periodontology, Araraquara, São Paulo, Brazil
,
Celso Eduardo Sakakura
2   Barretos Dental School, Barretos Educational Foundation, Brazil
,
Gulnara Scaf
3   UNESP – Univ Estadual Paulista, Araraquara Dental School, Department of Radiology, Araraquara, São Paulo, Brazil
,
Maria Teresa Pepato
4   UNESP – Univ Estadual Paulista, School of Pharmaceutical Sciences of Araraquara, Department of Clinical Biochemistry, Araraquara, Brazil
,
Elcio Marcantonio Jr.
1   UNESP – Univ Estadual Paulista, Araraquara Dental School, Department of Periodontology, Araraquara, São Paulo, Brazil
› Author Affiliations
Subject Editor:
Further Information

Publication History

Received15 December 2009
revised03 August 2010

accepted18 August 2010

Publication Date:
20 December 2017 (online)

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Introduction: This study evaluated the effect of Symphytum officinale in homeopathic potency (6cH), on the removal torque and radiographic bone density around titanium implants, inserted in rats tibiae.

Methods: Implants were placed in male rat tibiae, and the animals randomized to two groups (Control and S. officinale 6cH treated), which were evaluated at 7, 14, 28 and 56 days post-implantation. Radiographic bone density was measured at 6 points around the implant, using digital radiographic images, when implants were inserted and at sacrifice. Removal torque of the implants was also evaluated.

Results: Both removal torque and radiographic bone density evaluation showed that S. officinale 6cH treatment enhanced bone formation around the micro-implants, mainly at 14 days. At 56 days, the radiographic bone density was higher in the treated group.

Conclusions: We conclude that S. officinale 6cH enhances, principally at the early stages of osseointegration, bone formation around titanium implants in rats’ tibiae, based on radiographic and mechanical analysis.

Keywords

Radiography - Bone density - Torque - Symphytum officinale - Osseointegration - Titanium implants - Experimental - Homeopathy
 

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