CC BY-NC-ND 4.0 · J Neurosci Rural Pract 2011; 02(01): 056-061
DOI: 10.4103/0976-3147.80102
Review Article
Journal of Neurosciences in Rural Practice

Effect of plant extracts on Alzheimer’s disease: An insight into therapeutic avenues

M Obulesu
Capital College, Garden City Group of Institutions, Bangalore, India
Dowlathabad Muralidhara Rao
1  Srikrishnadevaraya University, Anantapur, India.
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26. September 2019 (online)


Alzheimer’s disease (AD) is a devastative neurodegenerative disorder which needs adequate studies on effective treatment options. The extracts of plants and their effect on the amelioration of AD symptoms have been extensively studied. This paper summarizes the mechanisms like acetylcholinesterase (AChE) inhibition, modifi cation of monoamines, antiamyloid aggregation effect, and antioxidant activity which are actively entailed in the process of amelioration of AD symptoms. These effects are induced by extracts of a few plants of different origin like Yizhi Jiannao, Moringaoleifera (Drumstick tree), Ginkgo Biloba (Ginkgo/Maidenhair tree), Cassia obtisufolia (Sicklepod), Desmodium gangeticum (Sal Leaved Desmodium), Melissa officinalis (Lemon Balm), and Salvia officinalis (Garden sage, common sage).