J Pediatr Intensive Care 2013; 02(02): 077-080
DOI: 10.3233/PIC-13053
Case Report
Georg Thieme Verlag KG Stuttgart – New York

Severe hypertriglyceridemia causing acute pancreatitis in a child with new onset type I diabetes mellitus presenting in ketoacidosis

Peter M. Wolfgram
Division of Pediatric Diabetes and Endocrinology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
,
Michael J. MacDonald
Division of Pediatric Diabetes and Endocrinology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
› Author Affiliations

Subject Editor:
Further Information

Publication History

01 November 2012

09 January 2013

Publication Date:
28 July 2015 (online)

Abstract

A 10-year-old girl presented with severe diabetic ketoacidosis and a hemoglobin A1c of 17.9%. On hospital day 2, after acidosis had improved, it worsened and she developed excruciating abdominal pain. Her serum triglycerides and lipase levels were found to be extremely high and ultrasound analysis of the pancreas was consistent with acute pancreatitis. She was diagnosed with acute pancreatitis secondary to hypertriglyceridemia. The pancreatitis resolved completely and 2 mo later her hemoglobin A1c was 8.2% and the serum triglycerides were normal. Severe hypertriglyceridemia from insulin deficiency causing pancreatitis in new onset type 1 diabetes mellitus is a rare but serious complication of diabetic ketoacidosis in children.