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CC BY 4.0 · Aorta (Stamford) 2013; 01(03): 210-217
DOI: 10.12945/j.aorta.2013.13-047
Basic Science for the Clinician
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Reasons to Investigate the Soluble Receptor for Advanced Glycation End-Product (sRAGE) Pathway in Aortic Disease

Abdullah Sarkar
1   Aortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, Connecticut
2   College of Medicine, Alfaisal University, Riyadh, Saudi Arabia
,
Kailash Prasad
3   Department of Physiology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
,
Bulat A. Ziganshin
1   Aortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, Connecticut
4   Department of Surgical Diseases # 2, Kazan State Medical University, Kazan, Russia
,
John A. Elefteriades
1   Aortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, Connecticut
› Institutsangaben
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Publikationsverlauf

31. Juli 2013

31. August 2013

Publikationsdatum:
28. September 2018 (online)

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Abstract

Aortic disease has a high rate of morbidity and mortality, and there are no documented screening methods to date. Yet biochemical research does show a significant link between soluble receptor for advanced glycation end-products (sRAGE) protein and cardiovascular disease. Therefore, it can be hypothesized that sRAGE plasma levels may help differentiate patients with aortic disease from the general population, which this paper will review and present.

Key Words

sRAGE - Aortic disease - Aortic aneurysm - Screening biomarker
 

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