Membrane-associated CD40L and sCD40L in atherothrombotic disease

Sunil X.Anand; Juan F. Viles-Gonzalez; Juan J. Badimon; Erdal Cavusoglu; Jonathan D. Marmur

doi:10.1160/TH03-05-0268

Thrombosis and Haemostasis, Inhaltsverzeichnis

Thromb Haemost 2003; 90(03): 377-384
DOI: 10.1160/TH03-05-0268

Review Article

Schattauer GmbH

Membrane-associated CD40L and sCD40L in atherothrombotic disease

Autor*innen

Sunil X.Anand

¹The Zena and Michael A.Weiner Cardiovascular Institute, Mount Sinai School of Medicine, New York, New York, USA
Juan F. Viles-Gonzalez

¹The Zena and Michael A.Weiner Cardiovascular Institute, Mount Sinai School of Medicine, New York, New York, USA
Juan J. Badimon

¹The Zena and Michael A.Weiner Cardiovascular Institute, Mount Sinai School of Medicine, New York, New York, USA
Erdal Cavusoglu

²Department of Medicine, Division of Cardiology, SUNY Health Science Center at Brooklyn, New York, USA
Jonathan D. Marmur

²Department of Medicine, Division of Cardiology, SUNY Health Science Center at Brooklyn, New York, USA

Abstract

Summary

Recent data suggests that CD40L is involved in the pathogenesis of atherothrombotic disease. This review will focus on the history of CD40L, its role in platelet-mediated pathogenesis of atherothrombotic disease, its association to clinical syndromes and procedures, and its role in determining plaque rupture.

Keywords

CD40L - atherothrombotic disease - platelets - extracellular matrix - matrix metalloproteinase

Volltext

Referenzen

References
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