Pyrazole-based artificial receptors have often been used in the recognition of ions,
but in the area of sugar recognition the potential of pyrazole-based recognition groups
has only been rarely examined. In this paper we describe the syntheses of twelve new
pyrazole-bearing compounds, which are all potentially applicable for use as carbohydrate
receptors. The prepared compounds enforce tripodal architecture and are based on a
triethyl- or trimethoxybenzene scaffold. Representative complexation studies with
selected carbohydrates showed interesting binding preferences of the new compounds.
Key words
tripodal receptors - pyrazole groups - carbohydrate recognition - triethylbenzene
scaffold - trimethoxybenzene scaffold
