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Synfacts 2008(9): 0909-0909
DOI: 10.1055/s-2008-1077993
DOI: 10.1055/s-2008-1077993
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag
Stuttgart ˙ New York
Synthesis of (±)-Cylindricine C
A. C. Flick, M. J. Arevalo Caballero, A. Padwa*
Emory University, Atlanta, USA
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
22. August 2008 (online)
Significance
Cylindricines attracted considerable synthetic interest due to their challenging perhydro pyrrolo[2,1-j]quinoline framework. A new access to (±)-cyclindricine C is reported using a Michael addition-dipolar cycloaddition sequence to construct the indolizidine core.