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DOI: 10.1055/s-2008-1045521
© 1994 F. Enke Verlag Stuttgart
Blaue Nävi der Konjunktiva
Blue Nevi of the Conjunctiva* Frau Dr. med. Gunda Nagel (2. Univ. Augenklinik Wien, Vorstand: Prof. Dr. med. H. Slezak) hospitierte vom 1. 3. 1994 bis zum 30. 4. 1994 im Ophthalmo-Pathologischen Labor der Augenklinik mit Poliklinik der Universität Erlangen-NürnbergPublikationsverlauf
Manuskript eingegangen am 31. 7. 94
in der vorliegenden Form angenommen am 5. 8. 94
Publikationsdatum:
08. Februar 2008 (online)
Summary
Patient and methods A 54-year-old man presented with multifocal pigmentations of the left bulbar and palpebral conjunctiva. He had first noticed these changes 5 years ago without any evidence of progression. The pigmented lesions were located in the plica, caruncle, the lower fornix and the mucocutaneous junction of the lower lid. The right cornea showed a focal superficial scar paracentrally due to a herpes simplex keratitis in 1970. Visual acuity was 20/20, otherwise the eyes were unremarkable. Biopsies were performed in all areas. One year after surgery, there was no recurrence of the lesions.
Microsopy Histopathologically, the conjunctival epithelium is essentially unremarkable. The substantia propria display mostly uniformly pigmented spindle-shaped melanocyte cells. Many cells contain coarsely clumped melanin granules. Other areas reveal poorly pigmented to unpigmented melanocytic cells, some of them with Schwannian features. Intranuclear vacuoles are commonly present. The tumor cells are often located in stromal areas displaying increased amounts of collagen. A few polyhydral melanophages are present within the lesion.
Diagnosis Biopsy A (plica) - blue nevus with areas of cellular blue nevus. Biopsy B (caruncle) - cellular blue nevus. Biopsy C (lower fornix) - cellular blue nevus. Biopsy D (mucocutaneous junction of left lower lid) - Blue nevus.
Schlüsselwörter
Blaue Nävi - Konjunktiva
Key words
Blue nevi - conjunctiva