ABSTRACT
Three consecutive cases of isolated pleural effusion in aneuploid fetuses are reported.
The presence of pleural effusion in trisomy 13 had not been described in the literature
previously. Early development of pleural effusion is usually associated with fetal
hydrops and carries a poor prognosis. Late development of pleural effusion can be
treated in utero. A karyotype should be performed in all cases of pleural effusion
prior to in utero pleuroamniotic shunting.
