ABSTRACT
Antenatal sonography in two cases demonstrated cerebral ventriculomegaly and decreased
head circumference, subsequently found to be secondary to cytomegalovirus (CMV) infection.
In both cases, the lateral ventricles were enlarged and lissencephaly was diagnosed
in the neonatal period. The findings of ventriculomegaly and decreased head circumference
on antenatal sonography warrant further investigation for CMV via amniotic fluid cultures
or fetal blood, given the poor prognosis in infants with symptomatic infection.