Am J Perinatol 1993; 10(2): 97-100
DOI: 10.1055/s-2007-994636

© 1993 by Thieme Medical Publishers, Inc.

Mathematical Modeling of Fetal Organ Growth Using the Rossavik Growth Model: II. Adrenal Gland

Toshiyuki Hata, Russell L. Deter, Hiroko Nagata, Ken Makihara, Kohkichi Hata, Manabu Kitao
  • Department of Obstetrics and Gynecology, Shimane Medical University, Izumo, Japan, and Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas
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Publication History

Publication Date:
04 March 2008 (online)


Growth of the fetal adrenal gland has been monitored by measurements of the circumference (AGC) and area (AGA) of the adrenal gland from 16 to 40 weeks menstrual age. Growth curves for these parameters have been determined using a Rossavik growth curve models [P = c(t)k+5W]. R2 values of 86.2 and 91.1% were obtained for AGC and AGA, respectively. Variability analysis indicated a progressive increase in variability with menstrual age for these two parameters. Variability data were used with the growth curve models to determine standard curves for AGC and AGA. These standard curves provide a superior means for evaluating the adrenal growth in the fetus and the fetal status in utero in high-risk pregnancies.