Am J Perinatol 1998; 15(5): 281-286
DOI: 10.1055/s-2007-993943

© 1998 by Thieme Medical Publishers, Inc.

Obstetrical Factors Governing the Etiopathogenesis of Lambdoid Synostosis

Hrayr K. Shahinian1 , Ronald Jaekle2 , Richard H. Suh, Reza Jarrahy, Vivian C. Aguilar, Michael Soojian
  • 1Director, Division of Skull Base Surgery, Skull Base Institute, Cedars-Sinai Medical Center
  • 2Assistant Professor of Obstetrics and Gynecology, Department of Obstetrics, Gynecology and Reproductive Medicine, State University of New York at Stony Brook
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Publication History

Publication Date:
04 March 2008 (online)


Lambdoid synostosis results in skull deformities of varying degrees characterized by occipital flattening over the involved suture and other compensatory changes in skull shape. Such changes include contralateral occipital bossing, contralateral frontal flattening, ipsilateral frontal bossing, and ipsilateral anteroinferior displacement of the pinna (ear shearing). These deformities tend to worsen during the first year of life. The etiology has been attributed to genetic factors and primary disorders of bone growth, in addition to secondary effects of other diseases and modulators of the in utero environment. To determine causal factors in the development of lambdoid synostosis, the authors reviewed medical records of the mothers of 13 children with lambdoid synostosis who were treated at the University Medical Center of the State University of New York at Stony Brook. Pre- and perinatal events, prior obstetrical, gynecological, medical, social, and family histories were considered. Births of normal infants immediately prior to and just after the affected babies were born were selected as controls. There is a significant association between increased duration of the first stage of labor and the development of lambdoid synostosis. Furthermore, our results indicate that this condition has a predilection toward male infants, and may be associated with preterm labor.