ABSTRACT
A 33-day-old male infant who developed central diabetes insipitus as a complication
of congenital toxoplasmosis is presented. He had polyuria and hypernatremia on admission
and responded to Intranasal desmopressin acetate with the normalization of abovementioned
findings. Computed tomographic (CT) scan of the brain showed obstructive hydrocephaly
with periventricular and right basal ganglion calcification. CT scan of the pituitary
gland, thyroid function tests, and serum cortisol levels were all normal. This is
the first report of isolated diabetes insipitus with congenital toxoplasmosis in literature
and central diabetes insipitus should be remembered if polyuria and hypernatremia
develops in a patient with congenital toxoplasmosis.
Keywords
Congenital toxoplasmosis - diabetes insipitus
