Am J Perinatol 1998; 15(3): 191-192
DOI: 10.1055/s-2007-993924

© 1998 by Thieme Medical Publishers, Inc.

Central Diabetes Insipitus in a Patient with Congenital Toxoplasmosis

Nihal Oygür1 , Gülsün Yilmaz1 , Can Özkaynak2 , Ayfer Gür Güven1
  • 1Division of Neonatology, Department of Pediatrics, Akdeniz University Medical School, Antalya, Turkey
  • 2Division of Neonatology, Department of Radiology, Akdeniz University Medical School, Antalya, Turkey
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Publication History

Publication Date:
04 March 2008 (online)


A 33-day-old male infant who developed central diabetes insipitus as a complication of congenital toxoplasmosis is presented. He had polyuria and hypernatremia on admission and responded to Intranasal desmopressin acetate with the normalization of abovementioned findings. Computed tomographic (CT) scan of the brain showed obstructive hydrocephaly with periventricular and right basal ganglion calcification. CT scan of the pituitary gland, thyroid function tests, and serum cortisol levels were all normal. This is the first report of isolated diabetes insipitus with congenital toxoplasmosis in literature and central diabetes insipitus should be remembered if polyuria and hypernatremia develops in a patient with congenital toxoplasmosis.