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Am J Perinatol 1999; 16(2): 61-63
DOI: 10.1055/s-2007-993837
ORIGINAL ARTICLE

© 1999 by Thieme Medical Publishers, Inc.

Isolated Dandy-Walker Malformation: Prenatal Diagnosis in Two Consecutive Pregnancies

Barbara Ulm, Martin R. Ulm, Josef Deutinger, Gerhard Bernaschek
  • Department of Obstetrics and Gynecology, Division of Prenatal Diagnosis and Therapy, University Hospital Vienna, Austria
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Publikationsdatum:
04. März 2008 (online)

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ABSTRACT

We report a family with recurrent Dandy-Walker malformation (DWM). The first offspring was found prenatally to have isolated DWM at 30 weeks' gestation. Ultrasonography at 19 weeks' gestation in the subsequent pregnancy revealed isolated DWM in both dizygotic twins. Chromosome analysis was normal in all three infants, and autopsy confirmed that no other congenital abnormalities were present. Evidence suggests that rare families transmit the disorder in an autosomal or X-linked recessive patterns, with a high recurrence risk.

Keywords

Prenatal ultrasonography - Posterior fossa cyst - Dandy-Walker malformation - familiar recurrence