Synfacts 2007(11): 1149-1149  
DOI: 10.1055/s-2007-991284
Synthesis of Materials and Unnatural Products
© Georg Thieme Verlag Stuttgart · New York

Cationic Pseudopolyrotaxanes with Cyclodextrins and Cucurbit[6]urils

Contributor(s): Timothy M. Swager, Gaku Fukuhara
C.-F. Ke, S. Hou, H.-Y. Zhang, Y. Liu, K. Yang, X.-Z. Feng*
Nankai University, Tianjin, P. R. of China
Further Information

Publication History

Publication Date:
23 October 2007 (online)

Significance

A series of pseudopolyrotaxanes 1-(0, 20, 40, 70, 100) were synthesized in order to detect their ability to induce DNA condensation. Compound 3 was synthesized through 2 and 6-[(6-amino­hexyl)amino]-6-deoxy-β-cyclodextrin (CD) di­chloride reported previously. Then, (0, 20, 40, 70, 100)% cucurbit[6]urils (CB[6]s) (calculated to the modified CD) were added to the aqueous solutions of 3 to form these novel 2D pseudopolyrotaxanes 1.