Selective Iron-Catalyzed Biaryl Coupling: Suppression of Homocoupling

Significance

The authors have found a useful method for selective iron-catalyzed biaryl coupling. Homocoupling is efficiently suppressed by applying a combination of FeF₃ and SiPr×HCl as catalyst system. The fluoride anion hereby plays a crucial role, since replacing FeF₃ with FeCl₃ proceeds with predominance of the homocoupling reaction.