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Int J Sports Med 2008; 29(9): 706-712
DOI: 10.1055/s-2007-989454
Physiology & Biochemistry

© Georg Thieme Verlag KG Stuttgart · New York

Prediction of Glucose Oxidation Rate during Exercise

M. P. Francescato1 , M. Zanier1 , F. Gaggioli1
  • 1Department of Biomedical Sciences and Technologies, University of Udine, Udine, Italy
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Publication History

accepted after revision December 5, 2007

Publication Date:
22 January 2008 (online)

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Abstract

Recently, the relationship between percentage maximal heart rate vs. glucose oxidation rate has been proposed as a tool for estimating glucose oxidation rate during exercise in insulin-dependent diabetic patients. The reliability of this relationship and its applicability to long-term exercise is evaluated. Eight healthy volunteers performed a graded cycloergometric exercise (10-min steps at 30, 50, 70, 90 % of ventilatory threshold). Heart rate and glucose oxidation rate (by indirect calorimetry) were measured during the last 5 min of each step. Volunteers underwent then three 1-hour constant intensity rides at 40, 60, 80 % of ventilatory threshold. Heart rate was recorded continuously; glucose oxidation rate was determined over 15-min periods. The percentage maximal heart rate vs. glucose oxidation rate relationship obtained from the graded exercise matched that previously reported. Independently of intensity, glucose oxidation rates observed during the 1-hr rides were linearly related to the estimated ones (R2 > 0.96, p < 0.001), being, however, progressively over-estimated in subsequent exercise periods. The proposed correction yields values close to the identity line (y = 1.001 · x; R2 = 0.974, p < 0.001), the difference between observed and “corrected” values amounting to 0.23 ± 2.17 mg · min−1 · kg−1. In conclusion, glucose oxidation rate can be estimated from heart rate, once proper correction factors are applied for long duration exercises.

Key words

exercise metabolism - type 1 diabetes - glycaemia - carbohydrate - clinical physiology

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Dr., MD Maria Pia Francescato

University of Udine
Department of Biomedical Sciences and Technologies

p.le M. Kolbe 4

33100 Udine

Italy

Phone: + 39 04 32 49 43 36

Fax: + 39 04 32 49 43 01

Email: MFrancescato@mail.dstb.uniud.it

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