Eur J Pediatr Surg 2007; 17(6): 431-432
DOI: 10.1055/s-2007-989221
Case Report

© Georg Thieme Verlag KG Stuttgart · New York

OK-432 as a Sclerosing Agent to Treat Wound-Healing Impairment

G. Fasching1 , M. Sinzig2
  • 1Department of Paediatric Surgery, General Hospital Klagenfurt, Klagenfurt, Austria
  • 2Department of Radiology, General Hospital Klagenfurt, Klagenfurt, Austria
Further Information

Publication History

received May 5, 2007

accepted May 23, 2007

Publication Date:
11 December 2007 (online)


We report on the application of OK-432 (picibanil) in a patient with prolonged wound healing impairment. A 13-year-old girl had suffered a polytrauma with a displaced fracture of the sacrum which required neurosurgical decompression of the sacral plexus. Postoperatively, a seroma with recurrent fistulation was seen. Excision of the wound, prolonged suction drainage and the instillation of hypertonic glucose solution did not have any effect over a period of four months postoperatively. Relying on our personal experience of the treatment of lymphangiomas using OK-432 we instilled OK-432 into the wound. Leakage stopped immediately, there was a regression of fluid accumulation and four weeks later the ultrasound examination was normal. The patient is still asymptomatic four years after treatment. OK-432 can be used effectively for the treatment of chronic wound healing impairment.


M.D. Günter Fasching

Head, Department of Paediatric Surgery
General Hospital Klagenfurt

St. Veiter Strasse 47

9026 Klagenfurt