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DOI: 10.1055/s-2007-989221
© Georg Thieme Verlag KG Stuttgart · New York
OK-432 as a Sclerosing Agent to Treat Wound-Healing Impairment
Publication History
received May 5, 2007
accepted May 23, 2007
Publication Date:
11 December 2007 (online)
Abstract
We report on the application of OK-432 (picibanil) in a patient with prolonged wound healing impairment. A 13-year-old girl had suffered a polytrauma with a displaced fracture of the sacrum which required neurosurgical decompression of the sacral plexus. Postoperatively, a seroma with recurrent fistulation was seen. Excision of the wound, prolonged suction drainage and the instillation of hypertonic glucose solution did not have any effect over a period of four months postoperatively. Relying on our personal experience of the treatment of lymphangiomas using OK-432 we instilled OK-432 into the wound. Leakage stopped immediately, there was a regression of fluid accumulation and four weeks later the ultrasound examination was normal. The patient is still asymptomatic four years after treatment. OK-432 can be used effectively for the treatment of chronic wound healing impairment.
Key words
picibanil - OK‐432 - wound healing - seroma
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M.D. Günter Fasching
Head, Department of Paediatric Surgery
General Hospital Klagenfurt
St. Veiter Strasse 47
9026 Klagenfurt
Austria
Email: g.fasching@lkh-klu.at